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The binding of ADH to principal cells causes vesicles with aquaporin proteins to migrate to the interior of the cells.True false question.TrueFalse

Question

The binding of ADH to principal cells causes vesicles with aquaporin proteins to migrate to the interior of the cells.

True false question.
True
False

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Solution

Understanding the Question

The statement involves the function of Antidiuretic Hormone (ADH) in the context of renal physiology, specifically regarding how it affects aquaporin proteins in principal cells of the kidney.

Analysis of the Statement

  1. ADH Function: ADH is crucial for regulating water balance in the body. It promotes water reabsorption in the kidneys.
  2. Principal Cells: Located in the collecting ducts of the nephron, these cells respond to ADH.
  3. Aquaporins: These are water channel proteins that facilitate the passive movement of water across cell membranes. In the presence of ADH, these proteins are inserted into the luminal membrane of principal cells to increase water permeability.

Verification

When ADH binds to its receptors on principal cells, it triggers a signaling cascade that leads to the translocation of vesicles containing aquaporins to the cell surface, increasing water reabsorption from the urine back into the blood.

Conclusion

The statement is false because the binding of ADH does not cause vesicles to migrate to the interior of the cells; rather, it prompts them to be inserted into the cell membrane, increasing water permeability.

Final Answer

False.

This problem has been solved

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