1.What are the hypersensitivity types which are inmmunoglobulin mediated and which are cell mediated?

Hypersensitivity reactions are divided into four types: Type I, II, III and IV.

1. Type I, II, and III hypersensitivity reactions are immunoglobulin-mediated.

   • Type I hypersensitivity is mediated by Immunoglobulin E (IgE). This type of hypersensitivity is responsible for allergic reactions.

   • Type II hypersensitivity is mediated by Immunoglobulin G (IgG) and Immunoglobulin M (IgM). This type of hypersensitivity involves antibody-mediated cellular dysfunction.

   • Type III hypersensitivity is also mediated by Immunoglobulin G (IgG) and Immunoglobulin M (IgM). This type of hypersensitivity involves immune complex-mediated tissue injury.

2. Type IV hypersensitivity is cell-mediated. It is not mediated by immunoglobulins. Instead, it is mediated by T cells. This type of hypersensitivity is responsible for delayed type hypersensitivity reactions.