____________ is usually separated from the underlying tissue by an extracellular fibrous basement membrane.MuscleBoneEpitheliumBlood

The correct option is Epithelium.

Explanation

Epithelium is a type of tissue that lines the surfaces of organs and structures throughout the body, including the skin, blood vessels, organs, and cavities. It is characterized by a layer of cells that are closely packed together, and it is usually separated from the underlying connective tissue by a thin extracellular fibrous basement membrane. This basement membrane provides support and anchorage to the epithelium and acts as a barrier to regulate the movement of substances between the epithelium and underlying tissues.

Muscle, bone, and blood have different functions and structural characteristics that do not involve this specific relationship with the basement membrane.