Before B cells secrete antibodies they differentiate into: Stem cells Antigen presenting cells Plasma cells Macrophages T cells

Breakdown of the Problem

To determine the correct answer, we need to identify the differentiation pathway of B cells within the immune system.

Relevant Concepts

B cells originate from hematopoietic stem cells in the bone marrow. Upon activation, they differentiate into several cell types, primarily plasma cells, which are responsible for secreting antibodies.

Analysis and Detail

1. Stem Cells: B cells do arise from stem cells, but stem cells themselves are not a differentiation stage for B cells; they are the progenitors.
2. Antigen Presenting Cells: While some B cells can act as antigen presenting cells, this is not a form of differentiation for them; it is more of a function.
3. Plasma Cells: Upon encountering an antigen, activated B cells differentiate into plasma cells, which are specifically tasked with antibody production.
4. Macrophages: These are a type of immune cell that ingests pathogens and are derived from monocytes, not B cells.
5. T Cells: B cells and T cells develop from common progenitor cells but follow different pathways; T cells are not a stage in B cell differentiation.

Verify and Summarize

The key differentiation point for B cells that leads to antibody secretion is the transformation into plasma cells.

Final Answer

B cells differentiate into Plasma cells before secreting antibodies.