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Define the following term:a. Karyotypeb. Give examples of a male, female and down syndrome karyotypes

Question

Define the following term:

a. Karyotype

b. Give examples of a male, female and down syndrome karyotypes

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Solution

a. Karyotype: A karyotype is the number and visual appearance of the chromosomes in the cell nuclei of an organism or species. It is a test that identifies and evaluates the size, shape, and number of chromosomes in a sample of body cells.

b. Examples of Karyotypes:

  • Male Karyotype: A typical male karyotype would have 46 chromosomes, including one X and one Y chromosome (46, XY). This means there are 22 pairs of autosomes (non-sex chromosomes) and one pair of sex chromosomes.

  • Female Karyotype: A typical female karyotype would also have 46 chromosomes, but instead of a Y chromosome, there would be two X chromosomes (46, XX). This means there are 22 pairs of autosomes and one pair of sex chromosomes.

  • Down Syndrome Karyotype: Individuals with Down syndrome have an extra copy of chromosome 21, making a total of 47 chromosomes instead of the usual 46. This is often represented as 47, XX, +21 for females and 47, XY, +21 for males. This means there are 22 pairs of autosomes, one pair of sex chromosomes, and an extra chromosome 21.

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