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Which organelle is involved in detoxification of drugs in liver cells? Rough ER Smooth ER Golgi apparatus Lysosome

Question

Which organelle is involved in detoxification of drugs in liver cells?

  • Rough ER
  • Smooth ER
  • Golgi apparatus
  • Lysosome
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Solution

The organelle involved in detoxification of drugs in liver cells is the Smooth Endoplasmic Reticulum (Smooth ER).

Here's a step-by-step explanation:

  1. The Smooth ER is an organelle found in both animal cells and plant cells. An organelle is a subunit within a cell that has a specific function.

  2. The main function of the Smooth ER is to synthesize lipids, metabolize carbohydrates and steroids, and regulate calcium concentration, drug detoxification, and attachment of receptors on cell membrane proteins.

  3. In the context of liver cells, the Smooth ER plays a crucial role in detoxifying harmful substances that may enter the body.

  4. When a toxic substance enters a liver cell, the Smooth ER modifies it to make it less harmful. This is often done by adding a hydroxyl group to the substance, making it more soluble in water and easier for the body to remove.

  5. Therefore, the Smooth ER is the organelle that is involved in the detoxification of drugs in liver cells.

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