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The alleles of a heterozygous SNP can have different affinities for a transcription factor,

Question

The alleles of a heterozygous SNP can have different affinities for a transcription factor,

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Solution

This statement refers to the concept of Single Nucleotide Polymorphisms (SNPs) and how genetic variation can affect the binding affinity of transcription factors to specific DNA sequences.

In a heterozygous SNP, there are two different alleles present at a specific location in the genome. Depending on the sequence of these alleles, a transcription factor may exhibit different binding affinities to each allele. This can have significant implications for gene expression and regulation, as the differential binding may influence the transcriptional output of genes associated with the SNP.

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