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Identify the type of linkage found between two amino acids when they combine to form a dipeptide.

Question

Identify the type of linkage found between two amino acids when they combine to form a dipeptide.

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Solution

Type of Linkage in Dipeptide Formation

  1. Amino Acids and Dipeptides: Amino acids are the building blocks of proteins. When two amino acids combine, they form a dipeptide.

  2. Linkage Type: The type of linkage that forms between the two amino acids during this process is called a peptide bond.

  3. Formation Process: The peptide bond is a covalent bond that occurs through a condensation (or dehydration synthesis) reaction. During this reaction, the carboxyl group (-COOH) of one amino acid reacts with the amino group (-NH2) of another, leading to the release of a water molecule and the formation of the bond.

  4. Chemical Structure: The peptide bond can be represented by the following reaction:

    Amino Acid 1(R1-NH2-C(=O)-)+Amino Acid 2(R2-NH2-C(=O)-)Dipeptide(R1-NHC(=O)-R2)+H2O \text{Amino Acid 1} (\text{R}_1\text{-NH}_2\text{-C(=O)-}) + \text{Amino Acid 2} (\text{R}_2\text{-NH}_2\text{-C(=O)-}) \rightarrow \text{Dipeptide} (\text{R}_1\text{-NH}-\text{C(=O)-R}_2) + \text{H}_2\text{O}

Summary

In summary, the peptide bond is the key linkage formed when two amino acids combine to create a dipeptide, involving a condensation reaction that releases water as a byproduct. This bond is fundamental to the structure of proteins.

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