How many electron carrier molecules (both NADH and FADH2) are made per glucose put in to glycolysis?

In the process of glycolysis, one glucose molecule is broken down to form two molecules of pyruvate. This process also produces energy-carrying molecules, including NADH and FADH2.

1. Glycolysis: During glycolysis, one molecule of glucose (which has six carbons) is broken down into two molecules of pyruvate (each with three carbons). In the process, two NADH molecules are produced. So, for each glucose molecule that undergoes glycolysis, two NADH molecules are made.

2. Transition Reaction: Each pyruvate then goes through a transition reaction to form Acetyl CoA. During this reaction, another NADH is produced. Since two pyruvates are formed from one glucose, this step produces two NADH molecules per glucose.

3. Krebs Cycle: Each Acetyl CoA then enters the Krebs cycle. For each round of the Krebs cycle, one FADH2 and three NADH are produced. Since two Acetyl CoA molecules are produced per glucose, this means the Krebs cycle produces two FADH2 and six NADH per glucose.

So, in total, per glucose molecule, glycolysis and subsequent processes produce 2 (from glycolysis) + 2 (from transition reaction) + 6 (from Krebs cycle) = 10 NADH molecules and 2 FADH2 molecules. Therefore, a total of 12 electron carrier molecules are made per glucose put into glycolysis.