Write the protein sequence in one-letter code that would be synthesized. (1 mark) 5’-ATGGCTGGGTGCTTTTAA-3’
Question
Write the protein sequence in one-letter code that would be synthesized. (1 mark)
5’-ATGGCTGGGTGCTTTTAA-3’
Solution
The given sequence is a DNA sequence. To find the protein sequence, we first need to transcribe this DNA sequence into mRNA and then translate that mRNA into a protein sequence.
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Transcription (DNA to mRNA): The DNA sequence 5’-ATGGCTGGGTGCTTTTAA-3’ is transcribed into the mRNA sequence 5'-AUGGCU GGGUGCUUUUAA-3'. In RNA, T (thymine) is replaced by U (uracil).
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Translation (mRNA to protein): The mRNA sequence is then translated into a protein sequence using the genetic code. Each set of three nucleotides, called a codon, codes for one amino acid.
- AUG codes for Methionine (M)
- GCU codes for Alanine (A)
- GGG codes for Glycine (G)
- UGC codes for Cysteine (C)
- UUU codes for Phenylalanine (F)
- UAA is a stop codon, which signals the end of the protein sequence.
So, the protein sequence in one-letter code that would be synthesized is MAGCF.
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