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Write the protein sequence in one-letter code that would be synthesized. (1 mark)      5’-ATGGCTGGGTGCTTTTAA-3’

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Solution

The given sequence is a DNA sequence. To find the protein sequence, we first need to transcribe this DNA sequence into mRNA and then translate that mRNA into a protein sequence.

  1. Transcription (DNA to mRNA): The DNA sequence 5’-ATGGCTGGGTGCTTTTAA-3’ is transcribed into the mRNA sequence 5'-AUGGCU GGGUGCUUUUAA-3'. In RNA, T (thymine) is replaced by U (uracil).

  2. Translation (mRNA to protein): The mRNA sequence is then translated into a protein sequence using the genetic code. Each set of three nucleotides, called a codon, codes for one amino acid.

  • AUG codes for Methionine (M)
  • GCU codes for Alanine (A)
  • GGG codes for Glycine (G)
  • UGC codes for Cysteine (C)
  • UUU codes for Phenylalanine (F)
  • UAA is a stop codon, which signals the end of the protein sequence.

So, the protein sequence in one-letter code that would be synthesized is MAGCF.

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