Patients with excess fat are more likely to require larger therapeutic doses of which vitamin? A.Vitamin B1B.Vitamin CC.Vitamin DD.Vitamin B3

Break Down the Problem

1. Identify the vitamins listed in the options:
   • A. Vitamin B1
   • B. Vitamin C
   • C. Vitamin D
   • D. Vitamin B3
2. Understand the relationship between body fat and vitamin requirements.

Relevant Concepts

1. Fat-soluble vitamins (like Vitamin D) tend to be stored in body fat.
2. Patients with excess fat may require adjustments in dosage for fat-soluble vitamins compared to water-soluble vitamins.

Analysis and Detail

1. Vitamin D is a fat-soluble vitamin, meaning it can become sequestered in body fat.
2. Individuals with higher fat levels may have lower bioavailability of Vitamin D because it gets trapped in fat tissue, leading to a need for larger doses to achieve therapeutic levels.
3. Water-soluble vitamins (like B1, C, and B3) do not have this fat-sequestration issue and typically do not require increased doses based on body fat.

Verify and Summarize

Considering the above analysis, while all vitamins play essential roles in health, Vitamin D's relationship with body fat makes it the most likely candidate to require larger doses in patients with excess fat.

Final Answer

C. Vitamin D