________________ has a DNA dependent RNA polymerase activity.Select one:A.TopoisomeraseB.LigaseC.DNA polymerase IIID.HelicaseE.Primase

Break Down the Problem

1. Identify the question's focus: the enzyme that possesses DNA-dependent RNA polymerase activity.
2. Evaluate the options provided.

Relevant Concepts

DNA-dependent RNA polymerase is an enzyme that synthesizes RNA from a DNA template. It plays a crucial role in transcription, the first step in gene expression. Only specific enzymes are responsible for this function.

Analysis and Detail

1. Topoisomerase: Primarily involved in altering the supercoiling of DNA but does not synthesize RNA.
2. Ligase: Enzyme that joins two DNA strands together but is not involved in RNA synthesis.
3. DNA polymerase III: Functions primarily in DNA replication, synthesizing DNA rather than RNA.
4. Helicase: Unwinds the DNA double helix, but does not synthesize RNA.
5. Primase: Synthesizes short RNA primers that provide a starting point for DNA synthesis, and also possesses DNA-dependent RNA polymerase activity.

Verify and Summarize

From the analysis, it is evident that Primase is the only enzyme among the options that can perform DNA-dependent RNA polymerase activity, specifically by synthesizing RNA primers for DNA replication.

Final Answer

E. Primase