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Which of the following proteins are considered to be tumour suppressor proteins? Group of answer choices Rb Cdk4 Ras Cyclin D

Question

Which of the following proteins are considered to be tumour suppressor proteins?

  • Rb
  • Cdk4
  • Ras
  • Cyclin D
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Solution

The protein considered to be a tumor suppressor protein among the given choices is Rb.

Here's a step-by-step explanation:

  1. Tumor suppressor proteins are a type of protein that regulates cell division and prevents the formation of cancer. They do this by controlling cell growth, repairing DNA mistakes, and telling cells when to die (a process known as apoptosis or programmed cell death).

  2. Rb, or Retinoblastoma protein, is a tumor suppressor protein. It is named after a cancer in which it was first discovered - Retinoblastoma. It plays a crucial role in regulating the cell cycle, halting cell division in response to damaged or unfavorable conditions.

  3. Cdk4, Cyclin D, and Ras, on the other hand, are not tumor suppressor proteins. Cdk4 and Cyclin D are proteins involved in cell cycle regulation, but they are not classified as tumor suppressors. Instead, they are often overactive in many types of cancer. Ras is a type of protein called a proto-oncogene. When mutated, it can become an oncogene, which can cause normal cells to become cancerous.

So, among the given choices, Rb is the tumor suppressor protein.

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