Knowee
Questions
Features
Study Tools

An electrophoretic separation of lactate dehydrogenase isoenzyme that demonstrates elevation in LD-1 greater than LD-2 could be indicative of:

Question

An electrophoretic separation of lactate dehydrogenase isoenzyme that demonstrates elevation in LD-1 greater than LD-2 could be indicative of:

🧐 Not the exact question you are looking for?Go ask a question

Solution

An elevation in LD-1 greater than LD-2 in an electrophoretic separation of lactate dehydrogenase isoenzyme could be indicative of a myocardial infarction, also known as a heart attack.

Here's a step-by-step explanation:

  1. Lactate dehydrogenase (LDH) is an enzyme found in almost all body tissues, but only released into the bloodstream when there's tissue damage.

  2. LDH is made up of five isoenzymes, which can be separated by electrophoresis. These isoenzymes are LD-1, LD-2, LD-3, LD-4, and LD-5.

  3. Under normal conditions, the LD-1 level is lower than the LD-2 level in the blood.

  4. However, when a heart attack occurs, heart cells are damaged and release their LDH. The LDH from heart cells is primarily LD-1.

  5. Therefore, after a heart attack, the LD-1 level in the blood can become higher than the LD-2 level. This is known as a "flipped LDH pattern" and is a strong indicator of a recent heart attack.

  6. So, an electrophoretic separation of lactate dehydrogenase isoenzyme that shows an elevation in LD-1 greater than LD-2 could be indicative of a myocardial infarction.

This problem has been solved

Similar Questions

A dehydrogenase enzyme belongs to which classification?Question 11Select one:a.hydrolaseb.oxidoreductasec.ligased.lyase

The activity of this enzyme is the main determinant of the rate of mitochondrial fatty acid oxidation:Group of answer choicesCPTPDHHAD

LDH and CYP enzymes are most likely to bind which substrates, respectively?A.NAPQI and APAPB.Lactate and APAPC.NAPQI and GSHD.Lactate and GSH

etabolic acidosis is associated with decreased plasma level of(A) bicarbonate(B) lactate(C) oxygen(D) urea

Which of the following protein act as enzymes?ans.InsulinAll of the aboveHaemoglobinIsomerase

1/1

Upgrade your grade with Knowee

Get personalized homework help. Review tough concepts in more detail, or go deeper into your topic by exploring other relevant questions.