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In a frameshift mutation, all of the amino acids before the shift are changed.Multiple ChoiceFalseTrue

Question

In a frameshift mutation, all of the amino acids before the shift are changed.

  • Multiple Choice
    • False
    • True
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Solution

Answer

The correct answer is True.

Explanation

In a frameshift mutation, there is an insertion or deletion of nucleotides that shifts the reading frame of the codons in the mRNA sequence. This change alters the entire downstream amino acid sequence from the point of mutation onward. As a result, all of the amino acids coded after the mutation are affected, and depending on the location of the mutation, it can also alter the amino acids before the shift. Therefore, the statement that "all of the amino acids before the shift are changed" can be considered True because once a frameshift occurs, the normal protein synthesis sequence is disrupted, and the translation can diverge significantly from the original sequence.

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