Which of the following glycolytic enzymes requires ATP as a substrate?Group of answer choicesHexokinaseAldolaseEnolasePyruvate kinase
Question
Which of the following glycolytic enzymes requires ATP as a substrate?
Group of answer choices
- Hexokinase
- Aldolase
- Enolase
- Pyruvate kinase
Solution
To determine which glycolytic enzyme requires ATP as a substrate, let's analyze each option provided:
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Hexokinase: This enzyme catalyzes the conversion of glucose to glucose-6-phosphate and requires ATP as a substrate. It is the first step in glycolysis where ATP is used to phosphorylate glucose.
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Aldolase: This enzyme catalyzes the conversion of fructose 1,6-bisphosphate into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. It does not require ATP.
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Enolase: This enzyme promotes the conversion of 2-phosphoglycerate to phosphoenolpyruvate, which does not involve ATP as a substrate.
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Pyruvate kinase: This enzyme catalyzes the conversion of phosphoenolpyruvate to pyruvate and generates ATP from ADP, but it does not use ATP as a substrate.
Final Answer
The glycolytic enzyme that requires ATP as a substrate is Hexokinase.
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