A cell that no longer has any developmental flexibility is said to beGroup of answer choicesepigenetictotipotentdementeddifferentiatedpluripotent

A cell that no longer has any developmental flexibility is said to be differentiated.

Here's why:

1. Differentiation is the process by which a cell changes from one cell type to another. Most commonly, the cell changes to a more specialized type.

2. When a cell differentiates, it may become a more specialized type of cell, such as a muscle cell, a red blood cell, or a neuron.

3. Once a cell has differentiated, it generally cannot change to another type of cell or revert back to an undifferentiated state. This means it has lost its developmental flexibility.

4. Therefore, a cell that no longer has any developmental flexibility is said to be differentiated.

The other terms mentioned in the question have different meanings:

• Epigenetic refers to changes in gene expression that are not caused by changes in the DNA sequence itself.
• Totipotent refers to a cell that has the capacity to form an entire organism.
• Demented is not a term typically used in cell biology.
• Pluripotent refers to a cell that has the capacity to develop into any of the three primary germ cell layers of the early embryo and therefore into all cells of the adult body, but not into the extra-embryonic tissues such as the placenta.