At pH of 5, an acid has a dissociating constant of 1.0 X 10-4 and distribution coefficient of 100.Find the distribution ratio of this acid.

Question

At pH of 5, an acid has a dissociating constant of 1.0 X 10-4 and distribution coefficient of 100.Find the distribution ratio of this acid.
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Solution 1

To find the distribution ratio (D) of the acid, we need to use the formula:

D = D' / (1 + Ka / [H+])

Where: D' is the distribution coefficient, Ka is the dissociation constant, and [H+] is the concentration of hydrogen ions.

Given: D' = 100, Ka = 1.0 x 10^-4, and pH = 5.

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