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ADA deficiency is caused due to theADeletionBTranslocationCSubstitutionDInversion

Question

ADA deficiency is caused due to the

  • A Deletion
  • B Translocation
  • C Substitution
  • D Inversion
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Solution

ADA deficiency is caused due to the Substitution. So, the answer is CSubstitution.

Here's a step-by-step explanation:

  1. ADA stands for Adenosine Deaminase, an enzyme that plays a crucial role in the immune system. It is involved in the breakdown of adenosine and deoxyadenosine, which are chemicals that can be harmful to the immune system.

  2. ADA deficiency is a genetic disorder. This means it is caused by abnormalities in the genes.

  3. The specific abnormality in ADA deficiency is a mutation in the ADA gene. This mutation can take several forms, but most commonly, it is a substitution mutation.

  4. A substitution mutation is a type of point mutation where one nucleotide in a DNA sequence is replaced with another. If the ADA gene has a substitution mutation, it may not be able to produce the ADA enzyme correctly, leading to ADA deficiency.

  5. Therefore, ADA deficiency is caused by a substitution mutation in the ADA gene.

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