A mutation converts an AGA codon to a TAA codon . This mutation is a:Termination mutationNoncoding mutationNonsense mutationMissense mutation
Question
A mutation converts an AGA codon to a TAA codon. This mutation is a:
- Termination mutation
- Noncoding mutation
- Nonsense mutation
- Missense mutation
Solution
To determine the type of mutation that converts an AGA codon to a TAA codon, let's analyze the codons:
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Understanding the Codons:
- AGA codon corresponds to the amino acid Arginine (Arg).
- TAA codon is a stop codon (specifically UAA in RNA), which signals termination of protein synthesis.
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Types of Mutations:
- Termination Mutation: Typically refers to a mutation that introduces a stop codon.
- Noncoding Mutation: Refers to a mutation that does not affect the coding sequence of a gene.
- Nonsense Mutation: This is a specific type of mutation where a codon that codes for an amino acid is changed into a stop codon, leading to premature termination of the protein.
- Missense Mutation: A mutation resulting in a codon that codes for a different amino acid.
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Identification:
- Since the AGA (Arg) is converted to TAA (stop), the function of the gene product is likely to be truncated, resulting in a shorter, likely nonfunctional protein.
Conclusion
This mutation is classified as a Nonsense mutation because it changes a codon for an amino acid into a stop codon, resulting in early termination of protein synthesis.
Similar Questions
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