Which of the following is used to convert an ester to an amide?Select answer from the options belowSodium cyanideAcetic anhydrideROH, pyridineAmmonia
Question
Which of the following is used to convert an ester to an amide?
Select answer from the options below:
- Sodium cyanide
- Acetic anhydride
- ROH, pyridine
- Ammonia
Solution
The correct answer is Ammonia.
Here is the step by step process:
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An ester is an organic compound where the hydrogen in the carboxyl group is replaced by a hydrocarbon.
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An amide is an organic compound that contains a carbonyl group (C=O) attached to a nitrogen atom.
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The conversion of an ester to an amide involves the reaction of the ester with ammonia (NH3).
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In this reaction, the ester's carbonyl carbon is attacked by the lone pair of electrons on the nitrogen atom of the ammonia.
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This results in the formation of a tetrahedral intermediate, which then collapses to release a molecule of alcohol.
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The remaining product is an amide, which has replaced the ester's alkoxy group (R-O) with an amino group (NH2).
So, the correct answer is Ammonia.
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