Reacting an amine with an acid anhydride will produce?Group of answer choicesan amide and a carboxylic acidan amide and HCla saltan ammonium ion and OH-
Question
Reacting an amine with an acid anhydride will produce?
- Group of answer choices
- an amide and a carboxylic acid
- an amide and HCl
- a salt
- an ammonium ion and OH<sup>-</sup>
Solution
Reacting an amine with an acid anhydride will produce an amide and a carboxylic acid.
Here's a step-by-step explanation:
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An acid anhydride is a compound that has two acyl groups bonded to the same oxygen atom.
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An amine is a compound with a nitrogen atom attached to one or more alkyl groups.
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When an amine reacts with an acid anhydride, a nucleophilic substitution reaction occurs. The nitrogen atom in the amine acts as a nucleophile, or electron pair donor, and attacks the electrophilic carbon atom in the acid anhydride.
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This reaction forms a tetrahedral intermediate, which then collapses to expel the weakest base. In this case, the weakest base is a carboxylate ion, which picks up a proton from the amine to form a carboxylic acid.
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The final products of this reaction are an amide (from the reaction of the amine with the acyl group) and a carboxylic acid.
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