The antibody class that is most closely associated with immediate allergic reactions is Blank______.Multiple choice question.IgMIgAIgGIgE

Break Down the Problem

1. Identify the classes of antibodies provided in the options.
2. Determine which antibody class is associated with immediate allergic reactions.

Relevant Concepts

The main antibody classes include:

• IgM: Usually involved in the primary immune response.
• IgA: Primarily found in mucosal areas, protecting against pathogens.
• IgG: The most abundant antibody in the blood, critical for opsonization and neutralization.
• IgE: Specifically associated with allergic reactions and responses against parasitic infections.

Analysis and Detail

IgE is the antibody class that binds to allergens and triggers histamine release from mast cells and basophils, leading to immediate allergic reactions such as anaphylaxis, hay fever, and asthma.

Verify and Summarize

By reviewing the roles of the different immunoglobulin classes, it is confirmed that IgE is the one most closely associated with immediate allergic reactions.

Final Answer

IgE