Hemophilia is a sex-linked recessive disorder.  A man with hemophilia mates with a woman who is a carrier for the disease.  What is the genotype of the woman?

Genotype of the Woman

1. Break Down the Problem

   • Understand that hemophilia is a sex-linked recessive disorder associated with the X chromosome.
   • Identify the genotypes of the individuals involved: the man with hemophilia and the carrier woman.

2. Relevant Concepts

   • Males have one X and one Y chromosome (XY).
   • Females have two X chromosomes (XX).
   • Since hemophilia is recessive, a person must have two copies of the hemophilia allele (X^h X^h) to express the condition. A carrier female has one normal allele and one hemophilia allele (X^H X^h).

3. Analysis and Detail

   • The man with hemophilia must have the genotype X^h Y, meaning his X chromosome carries the allele for hemophilia.
   • The woman is a carrier, which means she has one normal allele (X^H) and one allele for hemophilia (X^h). Thus, her genotype is X^H X^h.

4. Verify and Summarize

   • Confirm that the woman carries the normal allele and one that carries the hemophilia trait.
   • In summary, the woman in this scenario is a carrier for hemophilia.

Final Answer

The genotype of the woman is X^H X^h (carrier for hemophilia).