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The breakdown of the nuclear envelope is due to the phosphorylation of which protein by a CDK?Group of answer choicesPhosphatasecyclinDBRPLamin

Question

The breakdown of the nuclear envelope is due to the phosphorylation of which protein by a CDK?

Group of answer choices

  • Phosphatase
  • cyclin
  • DBRP
  • Lamin
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Solution

The breakdown of the nuclear envelope during cell division is primarily associated with the phosphorylation of lamins, a class of proteins that form the nuclear lamina. This phosphorylation process is mediated by cyclin-dependent kinases (CDKs), which are crucial for the regulation of the cell cycle.

  1. Phosphatase: This is an enzyme that removes phosphate groups; it is not responsible for the breakdown of the nuclear envelope.

  2. Cyclin: Cyclins are regulatory proteins that activate CDKs; they do not directly lead to the phosphorylation of proteins involved in nuclear envelope breakdown.

  3. DBRP: This option does not commonly relate to nuclear envelope breakdown.

  4. Lamin: This is the correct choice as lamins undergo phosphorylation by CDKs during mitosis, leading to the disassembly of the nuclear envelope.

Final Answer: Lamin

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