The breakdown of the nuclear envelope is due to the phosphorylation of which protein by a CDK?Group of answer choicesPhosphatasecyclinDBRPLamin
Question
The breakdown of the nuclear envelope is due to the phosphorylation of which protein by a CDK?
Group of answer choices
- Phosphatase
- cyclin
- DBRP
- Lamin
Solution
The breakdown of the nuclear envelope during cell division is primarily associated with the phosphorylation of lamins, a class of proteins that form the nuclear lamina. This phosphorylation process is mediated by cyclin-dependent kinases (CDKs), which are crucial for the regulation of the cell cycle.
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Phosphatase: This is an enzyme that removes phosphate groups; it is not responsible for the breakdown of the nuclear envelope.
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Cyclin: Cyclins are regulatory proteins that activate CDKs; they do not directly lead to the phosphorylation of proteins involved in nuclear envelope breakdown.
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DBRP: This option does not commonly relate to nuclear envelope breakdown.
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Lamin: This is the correct choice as lamins undergo phosphorylation by CDKs during mitosis, leading to the disassembly of the nuclear envelope.
Final Answer: Lamin
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