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The Shine-Dalgarno sequence is located on molecules and is important in the initiation of .

Question

The Shine-Dalgarno Sequence

The Shine-Dalgarno sequence is located on mRNA molecules and is important in the initiation of translation.

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Solution

The Shine-Dalgarno sequence is located on mRNA (messenger RNA) molecules and is important in the initiation of protein synthesis.

Here are the steps to explain this:

  1. The Shine-Dalgarno sequence is a ribosomal binding site in bacterial and archaeal messenger RNA, generally located around 8 bases upstream of the start codon AUG.

  2. The sequence helps recruit the ribosome to the mRNA to initiate protein synthesis by aligning the ribosome with the start codon.

  3. It does this by pairing with the rRNA (ribosomal RNA) in the small ribosomal subunit. The complementary sequences in the rRNA and the Shine-Dalgarno sequence bind, positioning the ribosome correctly.

  4. This ensures that the protein synthesis starts at the correct location on the mRNA.

  5. Once the ribosome is correctly positioned, the protein synthesis can begin with the reading of the first codon. This process continues until a stop codon is reached, and the newly synthesized protein is released.

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